Author

James Boris Gilchrist

Diamond Light SourceORCID 0000-0002-9814-4285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Casper BergeriD· 1 shared Daniel K. ClareiD· 1 shared Elaine M. L. HoiD· 1 shared Helena Jane MaieriD· 1 shared Joanna WellsiD· 1 shared Jonathan M. GrimesiD· 1 shared Luı́s M. A. PerdigãoiD· 1 shared Maria HarkiolakiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Casper BergerORCID

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2 papers

Recent·Most cited

Coronavirus spherules are supported by a novel triple-layer protein lattice

Patrick Morley Phillips, Joanna Wells, Naveen Mathew, Nicole Doyle, Sarah Keep, Parijat Majumder, James Boris Gilchrist, Philippa C. Hawes, Jonathan M. Grimes, Maria Harkiolaki, Daniel K. Clare, Helena Jane Maier

This study identifies a triple-layer protein lattice within coronavirus spherules and confirms a molecular pore in DMVs, providing insights into coronavirus replication structures.

bioRxiv · Oct 9, 2026 · PreprintMicrobiology

Adaptive Milling: imaging feedback-driven automated fabrication of consistently thin cryo-lamellae

Thomas S. Glen, Thomas M. Fish, Elaine M. L. Ho, Patrick Cleeve, Luı́s M. A. Perdigão, Nadisha Gamage, Ravi Teja Ravi, James Boris Gilchrist, Michele C. Darrow, Mark Basham, Maud Dumoux, Casper Berger

This paper introduces Adaptive Polishing, a machine learning-driven method for improving the consistency and thinness of cryo-lamellae during focused ion beam milling.

bioRxiv · Sep 22, 2026 · PreprintMolecular Biology