Author

Dhanya Thamaraparambil Jayaram

Cleveland Clinic Lerner College of MedicineORCID 0000-0002-3139-7157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Dennis J. StuehriD· 2 shared Pranjal BiswasiD· 2 shared Yue DaiiD· 2 shared Arnab GhoshiD· 1 shared Elizabeth A. SweenyiD· 1 shared Pranav SivaramiD· 1 shared Priya Das Sinha· 1 shared Saurav MisraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

Dennis J. StuehrORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 27, 2026

Soluble guanylyl cyclase subunits act as Hsp90 co-chaperones to ensure the expression and functional maturation of hemeproteins in mammalian cells

Pranjal Biswas, Yue Dai, Arnab Ghosh…·Dennis J. Stuehr

This study shows that sGC subunits act as Hsp90 co-chaperones to facilitate heme acquisition and functional maturation of apo-hemeproteins in mammalian cells.

DOI 10.64898/2026.08.26.747375

humanproteomics

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Cell BiologyNature CommunicationsPeer-reviewedAug 26, 2025

Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas…·Dennis J. Stuehr

The paper identifies FLVCR1b as the mitochondrial heme exporter that delivers heme to GAPDH and downstream hemeproteins in human cells.

17 citationstop 4%

humanproteomics

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