Jesse A. Brown

Functional network collapse in neurodegenerative disease

This study identifies functional network changes in neurodegenerative diseases using MRI data, linking brain atrophy to specific connectivity patterns and cognitive deficits.

A dynamic gradient architecture generates brain activity states

This study uses deep learning to analyze fMRI data and identifies dynamic spatial gradients that underlie brain activity states and functional connectivity.

Dynamic autonomic nervous system patterns differentiate human emotions and manifest in resting physiology

Salience network atrophy links neuron type-specific degeneration to loss of empathy in frontotemporal dementia

The paper links neuron type-specific TDP-43 pathology in the frontoinsular cortex to salience network atrophy and loss of empathy in frontotemporal dementia.

State and trait characteristics of anterior insula time-varying functional connectivity

The paper identifies four time-varying functional connectivity modes in the anterior insula that exhibit both state and trait characteristics, relating to empathy and brain connectivity patterns.