HOPX governs a molecular and physiological switch between cardiomyocyte progenitor and maturation gene programs
Clayton E. Friedman, Seth W. Cheetham, Richard J. Mills, Masahito Ogawa, Meredith A. Redd, Han Sheng Chiu, Sophie Shen, Yuliangzi Sun, Dalia Mizikovsky, Romaric Bouveret, Xiaoli Chen, Holly K. Voges, Scott Paterson, Jessica E. De Angelis, Stacey B. Andersen, , Nathan J. Palpant
This study identifies HOPX as a molecular switch regulating cardiomyocyte progenitor and maturation gene programs, linking it to cardiac function and genetic variation.
bioRxiv · Apr 17, 2022 · PreprintDevelopmental Biology