Benjamin M. Hogan

This study shows that mural cells are not required for BBB function in developing zebrafish but protect against hemorrhage-induced BBB breakdown in adults.

This study shows that target RNA abundance controls collateral activity of RfxCas13d in human cells and zebrafish embryos, with high abundance causing widespread degradation and toxicity.

This study shows integrin β1-Talin1 at focal adhesions drive uncontrolled endothelial cell enlargement in CCM vasculature, independent of KLF2/4.

This study identifies multiple cis-regulatory elements controlling prox1a expression in distinct lymphatic vascular beds in zebrafish.

This study uses single-cell transcriptomics to investigate Prox1's role in lymphatic endothelial cell fate specification and differentiation in zebrafish, identifying new transcriptional targets and regulatory mechanisms.

This study identifies HOPX as a molecular switch regulating cardiomyocyte progenitor and maturation gene programs, linking it to cardiac function and genetic variation.

This study identifies a genetic interaction between Pkd1 and Wnt5a in controlling lymphatic vascular morphogenesis in mice, showing mutual suppression of lymphatic defects.

This study uses a zebrafish Erk biosensor to live-image dynamic Erk-signalling events during regenerative angiogenesis, revealing sequential Ca2+- and Vegfr-dependent mechanisms.

The paper identifies junction-based lamellipodia (JBL) as structures driving endothelial cell movement during vascular remodeling, showing their dependence on F-actin and VE-cadherin.