Author

Carole Fruchart‐Gaillard

Commissariat à l'Énergie Atomique et aux Énergies AlternativesORCID 0000-0002-3149-4774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexandra EvagelidisiD· 1 shared Ali Ben Djoudi Ouadda· 1 shared Annik PratiD· 1 shared Aurélien ThureauiD· 1 shared Delia Susan‐ResigaiD· 1 shared Emmanuelle GirardiD· 1 shared Evelyne Cassar Lajeunesse· 1 shared Hervé NozachiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexandra EvagelidisORCID

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1 paper

Recent·Most cited

Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: functional regulation of LDLR levels

Carole Fruchart‐Gaillard, Ali Ben Djoudi Ouadda, Lidia Ciccone, Emmanuelle Girard, Sepideh Mikaeeli, Alexandra Evagelidis, Maïlys Le Dévéhat, Delia Susan‐Resiga, Evelyne Cassar Lajeunesse, Hervé Nozach, Oscar Henrique Pereira Ramos, Aurélien Thureau, Pierre Legrand, Annik Prat, Vincent Dive, Nabil Georges Seidah

This study determines the 3D structure of the PCSK9-CHRD-P1.40 complex and shows how CAP1 and HLA-C interact with PCSK9 to regulate LDLR degradation.

Molecular Metabolism · Dec 22, 2022Peer-reviewedMolecular Biology