ImmunologyEMBO Molecular MedicinePeer-reviewed
Retargeted adenoviruses for local IgA and CD47 blocker production as a novel cancer therapy
Mariya Chernyavska, Karen Patricia Hartmann, Marco Jansen…·Wouter P. R. Verdurmen
This paper develops a retargeted adenovirus system to produce IgA antibodies and CD47 blockers in tumors, enhancing innate immune responses and reducing tumor volume in mice.
DOI 10.1038/s44321-026-00477-7