Author

Kosuke Kawaguchi

Mie UniversityORCID 0000-0002-3161-7981Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Akio Mizutani· 1 shared Daisuke MorishitaiD· 1 shared Hidekazu TokuharaiD· 1 shared Hiroko YamakawaiD· 1 shared Hiroshi Banno· 1 shared Kosuke YusaiD· 1 shared Mariko TakanoiD· 1 shared Masakazu ToiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Akio Mizutani

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1 paper

Recent·Most cited

CDK12/13 inhibitor, CTX-439, suppresses tumor growth and potentiates BCL-2 family blockade

Hiroko Yamakawa, Raghda Khatab, Akio Mizutani, Shunsuke Ebara, Takaharu Hirayama, Sunao Tanaka, Yusuke Tarumoto, Midori Sugiyama, Seiichi Sugino, Mariko Takano, Hidekazu Tokuhara, Toshio Tanaka, Hiroshi Banno, Yasuyoshi Arikawa, Yukiko Fukui, , Kosuke Yusa

This study develops CTX-439, a CDK12/13 inhibitor, showing anti-tumor effects and resistance mechanisms, and proposes combining it with BCL-2 family inhibitors for cancer treatment.

bioRxiv · Feb 20, 2026 · PreprintCancer Biology