Author

Yusuke Tarumoto

Kyoto UniversityORCID 0000-0001-6652-9618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Kosuke YusaiD· 2 shared Seiichi Sugino· 2 shared Akio Mizutani· 1 shared Atsushi MochizukiiD· 1 shared Daisuke MorishitaiD· 1 shared Fumi Wagai· 1 shared Hidekazu TokuharaiD· 1 shared Hiroko YamakawaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Kosuke YusaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 20, 2026

CDK12/13 inhibitor, CTX-439, suppresses tumor growth and potentiates BCL-2 family blockade

Hiroko Yamakawa, Raghda Khatab, Akio Mizutani…·Kosuke Yusa

This study develops CTX-439, a CDK12/13 inhibitor, showing anti-tumor effects and resistance mechanisms, and proposes combining it with BCL-2 family inhibitors for cancer treatment.

2 citations

humanexperimental assay

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BioinformaticsbioRxivPreprintAug 23, 2023

Inference of gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations

Masato Ishikawa, Seiichi Sugino, Yoshie Masuda…·Atsushi Mochizuki

This paper introduces RENGE, a method for inferring gene regulatory networks from time-series scCRISPR data, which outperforms existing methods and produces GRNs consistent with known databases.

DOI 10.1101/2023.08.23.554254

humanscRNA-seq

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