Author

Xiaonan Liu

Drexel UniversityORCID 0000-0002-3181-8310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Kazuhito Toyo‐okaiD· 5 shared Sara M. BlazejewskiiD· 4 shared Sarah A. BennisoniD· 4 shared Kimberly J. DoughertyiD· 1 shared Ngoc T. HaiD· 1 shared Trevor H. Smith· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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5 shared papersNeuroscience

Kazuhito Toyo‐okaORCID

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5 papers

Recent·Most cited

PEDF peptides rescue defects in neurite morphogenesis and intracellular calcium response in cortical neurons from mice exposed to valproic acid

Xiaonan Liu, Kazuhito Toyo‐oka

PEDF peptides improve neurite formation and calcium response in VPA-exposed cortical neurons, suggesting potential therapeutic use for neurodevelopmental disorders.

bioRxiv · Sep 20, 2025 · PreprintNeuroscience

High-Throughput Kinase Inhibitor Screening Reveals Roles for Aurora and Nuak Kinases in Neurite Initiation and Dendritic Branching

Sara M. Blazejewski, Sarah A. Bennison, Xiaonan Liu, Kazuhito Toyo‐oka

The paper screens 493 kinase inhibitors to identify roles of Aurora and Nuak kinases in neurite initiation and dendritic branching using Neuro2a cells and primary cortical neurons.

Scientific Reports · Apr 14, 2021Peer-reviewedNeuroscience

Glutathione S-transferase Pi (Gstp) Proteins Regulate Neuritogenesis in the Developing Cerebral Cortex

Xiaonan Liu, Sara M. Blazejewski, Sarah A. Bennison, Kazuhito Toyo‐oka

This study identifies Gstp proteins' role in neurite initiation and elongation during cortical development, showing their regulation through JNK signaling.

Human Molecular Genetics · Jan 1, 2021Peer-reviewedNeuroscience

14-3-3 shuttles Activity-dependent neuroprotective protein to the cytoplasm to promote appropriate neuronal morphogenesis, cortical connectivity and calcium signaling

Sarah A. Bennison, Sara M. Blazejewski, Xiaonan Liu, Kazuhito Toyo‐oka

This study shows that Adnp is shuttled from the nucleus to the cytoplasm by 14-3-3ε, regulating neuronal morphology, connectivity, and calcium signaling in mice.

bioRxiv · May 26, 2020 · PreprintNeuroscience

PEDF-Rpsa-Itga6 signaling regulates cortical neuronal morphogenesis

Sara M. Blazejewski, Sarah A. Bennison, Ngoc T. Ha, Xiaonan Liu, Trevor H. Smith, Kimberly J. Dougherty, Kazuhito Toyo‐oka

This study identifies PEDF-Rpsa-Itga6 signaling as critical for cortical neuronal morphogenesis, with disruptions linked to neurodevelopmental disorders.

bioRxiv · Jan 6, 2020 · PreprintNeuroscience