Kimberly J. Dougherty

Long-term Connectivity between Spinal Cord Tissue Transplants and the Injured Phrenic Motor Network

This study shows that embryonic spinal cord transplants improve diaphragm function after cervical SCI but lose connectivity over time, reducing long-term effectiveness.

Lumbar spinal Shox2 interneurons receive monosynaptic excitatory input from the lateral paragigantocellular nucleus in the adult mouse

The paper demonstrates a direct monosynaptic excitatory connection from the lateral paragigantocellular nucleus to lumbar spinal Shox2 interneurons in adult mice.

Properties of rhythmogenic currents in spinal Shox2 interneurons across postnatal development

The paper investigates how rhythmogenic ionic currents and ion channel expression in spinal Shox2 interneurons change during postnatal development in mice.

Activity of spinal RORβ neurons is related to functional improvements following combination treatment after complete SCI

This study identifies RORβ neurons as a target to limit hyperreflexia and enhance locomotor function after spinal cord injury using combination treatment.

Postnatal maturation of serotonergic modulation of spinal RORβ interneurons in the medial deep dorsal horn

This study examines the postnatal maturation of serotonergic modulation in spinal RORβ interneurons, showing increased excitability and receptor responsiveness in juvenile mice compared to early neonates.

A distinct down state assembly in retrosplenial cortex during slow-wave sleep

The paper identifies a distinct neuronal subpopulation in the retrosplenial cortex that fires during slow-wave sleep Down states and is involved in memory consolidation.

Mitigating sTNF/TNFR1 activation on VGluT2+ spinal cord interneurons improves immune function after mid-thoracic spinal cord injury

Covert actions of epidural stimulation on spinal locomotor circuits

This study investigates how epidural stimulation affects spinal locomotor circuits after spinal cord injury, showing that early stimulation preserves circuit function.

The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice

The paper investigates the role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice, finding that V3 aLPNs mediate synchronization between diagonal limb rhythm generators for trot and promote left-right synchronization for gallop and bound.

Neural interactions in developing rhythmogenic spinal networks: Insights from computational modeling

This study develops a computational model to investigate how electrical and chemical synapses influence rhythmic bursting in Shox2 neurons during spinal locomotor activity generation.

PEDF-Rpsa-Itga6 signaling regulates cortical neuronal morphogenesis

This study identifies PEDF-Rpsa-Itga6 signaling as critical for cortical neuronal morphogenesis, with disruptions linked to neurodevelopmental disorders.