Kazuhito Toyo‐oka

PEDF peptides improve neurite formation and calcium response in VPA-exposed cortical neurons, suggesting potential therapeutic use for neurodevelopmental disorders.

The paper shows tau and MAP6 have opposing roles in neuronal development by regulating microtubule stability and dynamics in cultured neurons and in vivo.

The paper screens 493 kinase inhibitors to identify roles of Aurora and Nuak kinases in neurite initiation and dendritic branching using Neuro2a cells and primary cortical neurons.

This study identifies Gstp proteins' role in neurite initiation and elongation during cortical development, showing their regulation through JNK signaling.

This study shows that Adnp is shuttled from the nucleus to the cytoplasm by 14-3-3ε, regulating neuronal morphology, connectivity, and calcium signaling in mice.

This study identifies PEDF-Rpsa-Itga6 signaling as critical for cortical neuronal morphogenesis, with disruptions linked to neurodevelopmental disorders.