Nobuyoshi Akimitsu

The paper identifies mitophagy-induced mRNA granules (mitoRGs) that regulate cell fate during PINK1/Parkin mitophagy by controlling PGAM5 activity.

This study examines RNA synthesis and degradation rates in naked mole-rat and mouse fibroblasts, finding higher degradation rates in aging-related pathways in NMRs.

This study develops Dyrec-seq to measure transcription and RNA degradation rates simultaneously, revealing their relationship to gene function and response to stimuli.

The paper identifies 48 mRNAs targeted by PUM1-mediated decay and shows that DNA damage inhibits this decay to activate DNA repair.