Author

Rubesh Raja

Indian Institute of Science BangaloreORCID 0000-0002-3204-0061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Deepak Kumar SainiiD· 1 shared Devendra Pratap SinghiD· 1 shared Doraiswami RamkrishnaiD· 1 shared Gaurav D. SankheiD· 1 shared Lina Aboulmouna· 1 shared Mano Ram MauryaiD· 1 shared Narendra M. DixitiD· 1 shared P. J. Athira· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Deepak Kumar SainiORCID

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2 papers

Recent·Most cited

Systems BiologyBiophysical JournalPeer-reviewedDec 15, 2023

Modeling transcriptional regulation of the cell cycle using a novel cybernetic-inspired approach

Rubesh Raja, Sana Khanum, Lina Aboulmouna…·Doraiswami Ramkrishna

The paper introduces a cybernetic-inspired modeling framework to analyze the transcriptional regulation of the mammalian cell cycle, identifying functional network modules and predicting future cell cycles.

1 citation

humanbulk RNA-seq

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Systems BiologyNature CommunicationsPeer-reviewedJul 25, 2023

Sequestration of histidine kinases by non-cognate response regulators establishes a threshold level of stimulation for bacterial two-component signaling

Gaurav D. Sankhe, Rubesh Raja, Devendra Pratap Singh…·Deepak Kumar Saini

The paper shows that non-cognate response regulators sequester phosphorylated histidine kinases, establishing a threshold for bacterial two-component signaling to prevent over-response to weak signals.

23 citations

statistical model

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