NeuroscienceCell Reports MedicinePeer-reviewed
In vivo evidence that SORL1, encoding the endosomal recycling receptor SORLA, can function as a causal gene in Alzheimer's Disease
Olav M. Andersen, Nikolaj Bøgh, Anne Marlene Landau…·Charlotte Brandt Sørensen
This study shows that SORL1 haploinsufficiency in pigs mimics early AD biomarker changes without neurodegeneration, supporting its role as a causal gene in Alzheimer's disease.
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