Janet C Harwood

A genome-wide association study of 69,369 schizophrenia cases and 236,642 controls identifies 270 risk loci, prioritizes 130 genes, and links common and rare risk variants to neuronal synaptic biology.

The paper examines the developmental expression of genes related to voltage-gated cation channels and their association with psychiatric disorders, finding that gene expression patterns vary with age and disorder type.

The paper examines the genetic association of FMRP targets with schizophrenia, major depressive disorder, and bipolar disorder, finding enrichment for risk alleles and variants in these disorders.

The paper identifies LACTB2 and PLIN2 as novel AD risk genes through monocyte-specific transcriptome-wide association study.

The paper uses a novel gene-based analysis approach to identify three novel genes associated with Alzheimer’s disease using genome-wide association data.

The paper generates genome-wide nucleosome maps in human iPSCs and neuronal progenitor cells, finding that positioned nucleosomes are sparse and dynamic but influence gene expression through structural changes rather than local transcriptional organization.