Author

Shahinaz M. Gadalla

National Cancer InstituteORCID 0000-0002-3255-8143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Simon VerhulstiD· 2 shared Stacy S. DruryiD· 2 shared Alyssa R. LindroseiD· 1 shared Benedict PateniD· 1 shared Brenen W. PapenbergiD· 1 shared Camilo FernandeziD· 1 shared Casey L. DagnalliD· 1 shared Chi ZhangiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMolecular Biology

Simon VerhulstORCID

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Author profile →

3 papers

Recent·Most cited

Genetic regulation of TERT splicing contributes to reduced or elevated cancer risk by altering cellular longevity and replicative potential

Oscar Flórez-Vargas, Michelle Ho, Maxwell H. Hogshead, Chia-Han Lee, Brenen W. Papenberg, Kaitlin Forsythe, Kristine M. Jones, Wen Luo, Kedest Teshome, Cornelis Blauwendraat, Kimberley J. Billingsley, Mikhail Kolmogorov, Melissa Meredith, Benedict Paten, Raj Chari, , Ludmila Prokunina‐Olsson

This study identifies VNTR6-1 and rs10069690 as regulators of TERT splicing and expression, influencing cancer risk and telomere dynamics through altered telomerase isoform ratios.

medRxiv · Nov 4, 2024 · PreprintGenetic & Genomic Medicine

Effects of DNA extraction, DNA integrity, and laboratory on the precision of qPCR-based telomere length measurement - a multi-lab impartial study

Jue Lin, Simon Verhulst, Camilo Fernandez, Casey L. Dagnall, Shahinaz M. Gadalla, Waylon James Hastings, Tsung‐Po Lai, Idan Shalev, Ying Wang, Yun‐Ling Zheng, Elissa S. Epel, Stacy S. Drury

This study evaluates how DNA extraction methods and lab factors affect qPCR-based telomere length measurement precision across multiple labs.

bioRxiv · Dec 14, 2022 · PreprintMolecular Biology

Method comparison studies of telomere length measurement using qPCR approaches: a critical appraisal of the literature

Alyssa R. Lindrose, Lauren W. Y. McLester‐Davis, Renee Isabella Tristano, Leila Kataria, Shahinaz M. Gadalla, Dan T. A. Eisenberg, Simon Verhulst, Stacy S. Drury

This review evaluates qPCR-based telomere length measurement methods, finding poor methodologic reporting and statistical rigor in existing studies.

PLoS ONE · Jan 20, 2021Peer-reviewedMolecular Biology