Author

Arsalan Hassan

Broad InstituteORCID 0000-0002-3262-0277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:whole-exome sequencing· 4 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Muhammad AyubiD· 4 shared Carlos N. PatoiD· 3 shared James A. KnowlesiD· 3 shared Michele T. PatoiD· 3 shared Patrick F. SullivaniD· 3 shared Aarno V. PalotieiD· 2 shared Aiden Peter CorviniD· 2 shared Akena Dickens· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersGenetic & Genomic Medicine

Muhammad AyubORCID

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Author profile →

4 papers

Recent·Most cited

Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations

Calwing Liao, Robert Ye, Julia Sealock, Toni A. Boltz, Franjo Ivankovic, Hilary K. Finucane, Daniel P. Howrigan, Yijia Christiana Liu, F. Kyle Satterstrom, Arsalan Hassan, Melkam Alemayehu Kebede, Stella Gichuru, Rehema M. Mwende, Charles R. J. C. Newton, Nastassja Koen, , Benjamin M. Neale

medRxiv · Oct 5, 2026 · PreprintGenetic & Genomic Medicine

Analysis of Rare Coding Variation Identifies New Genetic Contributors to Schizophrenia

Julia Sealock, Connor Dowd, Calwing Liao, Robert Ye, Daniel P. Howrigan, F. Kyle Satterstrom, Chiara Auwerx, Soyeon Kim, Cong Huai, Lin He, Melkam Alemayehu Kebede, Stella Gichuru, Rehema M. Mwende, Charles R. J. C. Newton, Nastassja Koen, , Akena Dickens

Ultra-rare damaging coding variants in 87,959 schizophrenia cases and 150,587 controls implicate 40 genes (16 exome-wide, 24 at 5% FDR), half overlapping autism, developmental delay or bipolar genes.

bioRxiv · Sep 21, 2026 · PreprintGenetics✦ In-depth digest

Evaluation of imputation performance of multiple reference panels in a Pakistani population

Jiayi Xu, Dongjing Liu, Arsalan Hassan, Giulio Genovese, Alanna C. Cote, Brian Fennessy, Esther Cheng, Alexander W. Charney, James A. Knowles, Muhammad Ayub, Roseann Elizabeth Peterson, Tim B. Bigdeli, Laura M. Huckins

This study evaluates imputation performance of reference panels in a Pakistani population, finding that ex1KG outperforms TOPMed despite its smaller size.

Human Genetics and Genomics Advances · Dec 18, 2024Peer-reviewedGenetic & Genomic Medicine

Rare schizophrenia risk variant burden is conserved in diverse human populations

Dongjing Liu, Dara Meyer, Brian Fennessy, Claudia Feng, Esther Cheng, Jessica Johnson, You Jeong Park, Marysia-Kolbe Rieder, Steven Ascolillo, Agathe M. de Pins, Amanda L. Dobbyn, Dannielle S. Lebovitch, Emily Moya, Tan-Hoang Nguyen, Lillian Wilkins, , Alexander W. Charney

The paper investigates the conservation of rare schizophrenia risk variants across diverse populations and finds consistent burden in constrained genes.

medRxiv · Jan 3, 2022 · PreprintGenetic & Genomic Medicine