Author

Coco R. Beudeker

University Medical Center UtrechtORCID 0000-0002-3271-2462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Bart W. BardoeliD· 1 shared Dennis J. DoorduijniD· 1 shared Frerich M. MassoniD· 1 shared Kulsum Mehboob DawoodbhoyiD· 1 shared Michiel van der FlieriD· 1 shared Panagiotis Theofilidis· 1 shared Suzan H. M. RooijakkersiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Bart W. BardoelORCID

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1 paper

Recent·Most cited

Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae

Kulsum Mehboob Dawoodbhoy, Coco R. Beudeker, Panagiotis Theofilidis, Frerich M. Masson, Michiel van der Flier, Suzan H. M. Rooijakkers, Bart W. Bardoel, Dennis J. Doorduijn

This study shows that excessive C5 conversion in Klebsiella pneumoniae strains limits C9 polymerisation, preventing MAC-dependent killing, but adding C9 restores killing, indicating these strains are not truly resistant.

PLoS Pathogens · May 11, 2026Peer-reviewedImmunology