Novel insights into the structure and evolution of the human SAGA complex by affinity-ligand purification
Mylène Damilot, Thomas Schoeps, Làszlò Tora, Patrick Schultz, Luc Lebeau, Gábor Pápai, Adam Ben Shem
This study reports the high-resolution structure of the human SAGA complex, revealing how the SPL module and TAF6L/HEAT repeats are integrated into the complex and their functional implications.
bioRxiv · Jul 31, 2025 · PreprintBiochemistry