Author

Isabel E. Johnson

ORCID 0000-0002-3294-4423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:protein structure· 1

Frequent Co-Authors

C. B. Collins· 1 shared Chris LangsdorfiD· 1 shared Christos M. KougentakisiD· 1 shared Cyra K. Fung· 1 shared Darin J. Hildebrandt· 1 shared Darrin A. Lindhout· 1 shared Diana LiiD· 1 shared Eric D. Turtle· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

C. B. Collins

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintJan 12, 2025

Catalytic degradation of circulating targets with FcRn-mediated cycling LYTACs

Christos M. Kougentakis, Matthew J. Shurtleff, Rachel M. Lieser…·Nicholas A. Lind

This paper introduces cataLYTACs, a new therapeutic modality that efficiently and durably degrades circulating proteins like IgE in vitro and in vivo, outperforming traditional inhibitors.

19 citations

humanmouse