Author

Natalia Higuita‐Castro

The Ohio State UniversityORCID 0000-0002-3297-6281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Adam StreicheriD· 1 shared Alex Valentine· 1 shared Ana I. Salazar‐PuertaiD· 1 shared Andrea Tran· 1 shared Angelica HigueraiD· 1 shared Candice C. Askwith· 1 shared Christopher M. BobbaiD· 1 shared Colleen IsabelleiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Adam StreicherORCID

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2 papers

Recent·Most cited

Non-viral vasculogenic reprogramming restores cognition and mitigates pathology in Alzheimer's disease

Diego Alzate‐Correa, Jonathan P. Stranan, Maria Angelica Rincon‐Benavides, Natalia Areiza Mazo, Luis Fernando Narváez-Pérez, Shara Jaramillo-Garrido, Tracy Nguyen, Roma Patel, William R. Lawrence, Ludmila Diaz‐Starokozheva, Ana I. Salazar‐Puerta, Andrea Tran, Alex Valentine, Natalia Claire Mendonca, Olivia Seline, , Daniel F. Gallego-Perez

This study shows that non-viral reprogramming of fibroblasts to vasculogenic cells improves cognition and reduces pathology in Alzheimer's disease mouse models.

bioRxiv · Jan 24, 2026 · PreprintNeuroscience

Mechanosensitive activation of mTORC1 mediates ventilator induced lung injury during the acute respiratory distress syndrome

Hyunwook Lee, Qinqin Fei, Adam Streicher, Wenjuan Zhang, Colleen Isabelle, Pragi Patel, Hilaire Colletta Lam, Miguel Pinilla-Vera, Diana Patricia Amador-Munoz, Diana Barragan-Bradford, Angelica Higuera, Rachel K. Putman, Elizabeth P. Henske, Christopher M. Bobba, Natalia Higuita‐Castro, , Joshua A. Englert

This study shows that mTORC1 activation during mechanical ventilation worsens lung injury in ARDS and that inhibiting mTORC1 can prevent ventilator-induced lung injury.

bioRxiv · Mar 2, 2020 · PreprintMolecular Biology