The clinical and functional effects of TERT variants in myelodysplastic syndrome
Christopher R. Reilly, Mikko Myllymäki, Robert Allyn Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie M. Tesmer, Frederick D. Tsai, Christopher James Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen‐Huan Hu, Esther H. Orr, Maxine M. Chen, , Robert Coleman Lindsley
The paper identifies TERT rare variants in MDS patients, showing shorter telomeres, younger age at diagnosis, and worse survival, suggesting their role in MDS pathogenesis and transplant outcomes.
Blood · May 21, 2021Peer-reviewedGenetics