Author

Valerie M. Tesmer

University of MichiganORCID 0000-0002-7445-8407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jayakrishnan NandakumariD· 2 shared Christopher James GibsoniD· 1 shared Christopher R. ReillyiD· 1 shared Corey S. CutleriD· 1 shared Daniel J. DeAngeloiD· 1 shared Donna S NeubergiD· 1 shared Druha Karunakaran· 1 shared Esther H. OrriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Jayakrishnan NandakumarORCID

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2 papers

Recent·Most cited

A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric Proteins

Jonathan D. Williams, Valerie M. Tesmer, Sagarika Kannoly, Hiroki Shibuya, Jayakrishnan Nandakumar

The paper develops a data-analysis pipeline for HT-SELEX datasets to study DNA-binding properties of telomeric proteins, showing binding preferences for G-enriched sequences and secondary structures.

bioRxiv · Mar 7, 2026 · PreprintBiochemistry

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Christopher R. Reilly, Mikko Myllymäki, Robert Allyn Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie M. Tesmer, Frederick D. Tsai, Christopher James Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen‐Huan Hu, Esther H. Orr, Maxine M. Chen, , Robert Coleman Lindsley

The paper identifies TERT rare variants in MDS patients, showing shorter telomeres, younger age at diagnosis, and worse survival, suggesting their role in MDS pathogenesis and transplant outcomes.

Blood · May 21, 2021Peer-reviewedGenetics