Author

Shilpa Padmanaban

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1

Frequent Co-Authors

Ajin Park· 1 shared Christopher James GibsoniD· 1 shared Christopher R. ReillyiD· 1 shared Chun‐Kan CheniD· 1 shared Corey S. CutleriD· 1 shared Daniel J. DeAngeloiD· 1 shared Donna S NeubergiD· 1 shared Druha Karunakaran· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Ajin Park

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Author profile →

2 papers

Recent·Most cited

YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks

Ning Tsao, Patrick M. Lombardi, Ajin Park, Jennifer Olabode, Rebecca Rodell, Hua Sun, Shilpa Padmanaban, Joshua R. Brickner, Miaw-Sheue Tsai, Elizabeth A. Pollina, Chun‐Kan Chen, Nima Mosammaparast

This study shows that RNA damage can cause DNA breaks through R-loop formation, and YTHDC1-THOC prevents this by binding to m1A-modified RNAs.

bioRxiv · Mar 14, 2024Molecular Biology

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Christopher R. Reilly, Mikko Myllymäki, Robert Allyn Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie M. Tesmer, Frederick D. Tsai, Christopher James Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen‐Huan Hu, Esther H. Orr, Maxine M. Chen, , Robert Coleman Lindsley

The paper identifies TERT rare variants in MDS patients, showing shorter telomeres, younger age at diagnosis, and worse survival, suggesting their role in MDS pathogenesis and transplant outcomes.

Blood · May 21, 2021Peer-reviewedGenetics