Author

Zebin Xiao

University of PennsylvaniaORCID 0000-0002-3311-7403Unclaimed ORCID profile · follow to get notified of new preprints

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Zebin Xiao1 paper · University of Pennsylvania

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Carl H. JuneiD· 1 shared Charles‐Antoine AssenmacheriD· 1 shared Ellen PuréiD· 1 shared Estela Noguera-OrtegaiD· 1 shared John ScholleriD· 1 shared Leslie ToddiD· 1 shared Li Huang· 1 shared Lili HuangiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Carl H. JuneORCID

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1 paper

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedAug 22, 2023

Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors

Zebin Xiao, Leslie Todd, Li Huang…·Ellen Puré

This study shows that targeting FAP+CAFs in desmoplastic pancreatic tumors reduces stromal barriers, enhances T cell infiltration, and improves response to immunotherapy.

322 citationstop 1%

mousebulk RNA-seq

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