Homologous recombination mutant lethality differs between h- and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin
Peter Kolesár, S. A. Paliavoi, Barbora Štefanovie, Jan Josef Palecek
The paper shows that HR is essential for S. pombe survival in h-S strains but not h+N strains due to differences in mat1 DSB formation and heterochromatin regulation.
bioRxiv · Oct 13, 2025 · PreprintMolecular Biology