Jan Josef Palecek

This study identifies the structural basis of βKNL2 centromeric targeting and its role in plant-specific kinetochore assembly, showing its dependence on the SANTA domain and interactions with centromeric DNA and KNL2.

The paper shows that AtLa1 binds to telomerase RNA in Arabidopsis, similar to LARP7 in ciliates, suggesting conserved RNA biogenesis pathways between plants and ciliates.

This study identifies SUMOylation sites in KNL2 that are critical for its centromere targeting and interaction with CENH3 in Arabidopsis.

The paper shows that HR is essential for S. pombe survival in h-S strains but not h+N strains due to differences in mat1 DSB formation and heterochromatin regulation.

This paper introduces SMC6 hinge mutations in Physcomitrium patens and shows that G514R disrupts SMC5/6 interactions and gene targeting, while G517R has minimal effects.

This study identifies the role of PpNSE5 in binding distant regions of the PpSMC5/6 complex and its specific involvement in DNA repair.

This study characterizes the NSE6 subunit of the moss Physcomitrium patens SMC5/6 complex, identifying a conserved motif and functional roles in complex dynamics and DNA repair.

The paper identifies a functional relationship between the SAGA histone acetyltransferase module and SMC5/6 complex in facilitating chromatin accessibility at gene regions.

This paper investigates the role of Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6 complexes, showing their impact on complex stability and dynamics.