Author

Lucas Christian de Sousa‐Paula

National Institute of Allergy and Infectious DiseasesORCID 0000-0002-3379-1609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Lucas TirloniiD· 2 shared Stephen M. LuiD· 2 shared Brian J. SmithiD· 1 shared Jan KotáliD· 1 shared John F. AnderseniD· 1 shared José M. C. RibeiroiD· 1 shared Larissa Almeida MartinsiD· 1 shared Markus BergeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Lucas TirloniORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Ixochymostatin, a trypsin inhibitor-like (TIL) protein from Ixodes scapularis, inhibits chymase and impairs vascular permeability

Larissa Almeida Martins, Markus Berger, Jan Kotál, Stephen M. Lu, Lucas Christian de Sousa‐Paula, Brian J. Smith, Yixiang Zhang, John F. Andersen, Lucas Tirloni

This paper identifies ixochymostatin, a TIL protein from Ixodes scapularis, which inhibits chymase and reduces vascular permeability, aiding tick blood feeding.

International Journal of Biological Macromolecules · Nov 22, 2024Peer-reviewedBiochemistry

Exploring midgut expression dynamics: longitudinal transcriptomic analysis of adult female Amblyomma americanum midgut and comparative insights with other hard tick species

Stephen M. Lu, Lucas Christian de Sousa‐Paula, José M. C. Ribeiro, Lucas Tirloni

The paper analyzes the longitudinal transcriptome of A. americanum midgut during feeding stages and compares it with other tick species to identify conserved transcripts and dynamic expression patterns.

bioRxiv · Sep 20, 2024 · PreprintBioinformatics