Lucas Tirloni

The paper presents the first chromosome-level nuclear genome of Simulium vittatum, linking cytogenetic features to genome organization and evolution.

This study identifies m6A RNA methylation as an antiviral mechanism in mosquito cells by regulating serine proteases that influence Zika virus replication.

The paper identifies a neuroimmune response that enables rapid tick removal in guinea pigs and humans, independent of antibodies, offering a new strategy for preventing tick-borne diseases.

This study identifies epigenetic regulators in Rhipicephalus microplus and shows that DNA methylation inhibition affects mitochondrial function and cell proliferation during embryogenesis.

This paper identifies ixochymostatin, a TIL protein from Ixodes scapularis, which inhibits chymase and reduces vascular permeability, aiding tick blood feeding.

The paper analyzes the longitudinal transcriptome of A. americanum midgut during feeding stages and compares it with other tick species to identify conserved transcripts and dynamic expression patterns.

This study identifies tick saliva proteins injected during feeding using LC-MS/MS, finding 284 conserved proteins that may serve as vaccine targets.