Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Emmajay Sutherland, Christopher John Harding, Tancrede Martin Y Du Monceau De Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia A. Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster
This study characterizes the structure and mechanism of NdasCDO, a flavin-dependent cyclodipeptide oxidase, revealing its promiscuous substrate scope and reaction mechanism.
Nature Communications · Jan 24, 2025Peer-reviewedBiochemistry