Christopher John Harding

This study determines the crystal structure of PIVS409A, revealing how the Cap region autoinhibits PIV and how it becomes activated through an intramolecular process.

This study identifies Bd0967 as a C-terminal processing protease in Bdellovibrio bacteriovorus that degrades flagellins and regulates developmental progression.

The paper designs improved nucleoside 2'-deoxyribosyltransferase enzymes with enhanced catalytic efficiency and broad substrate promiscuity for generating diverse nucleoside products.

This study characterizes the structure and mechanism of NdasCDO, a flavin-dependent cyclodipeptide oxidase, revealing its promiscuous substrate scope and reaction mechanism.