Birgit Linkohr

Intraindividual longitudinal changes of the proteome reveal dynamic markers of biological aging

The paper develops a proteomic aging clock using longitudinal plasma proteomics data to show that biological aging is dynamically influenced by modifiable risk factors.

Novel and Known Genetic Players in Hypertension: From Gene Expression to Striking Insights

This study identifies novel and known genetic contributors to hypertension using RNA-seq and eQTL analyses, highlighting potential drug targets and pathways.

CODI: Enhancing machine learning-based molecular profiling through contextual out-of-distribution integration

CODI improves ML model generalization by integrating synthetic out-of-distribution data into molecular fingerprint datasets, enhancing classification accuracy in longitudinal clinical studies.