Author

Huan Shu

University of Massachusetts Chan Medical SchoolORCID 0000-0002-3395-2409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:Ribo-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Elisa R. DonnardiD· 2 shared Botao Liu· 1 shared Joel D. RichteriD· 1 shared Manuel G. GarberiD· 1 shared Ruijia WangiD· 1 shared Suna JungiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersGenomics

Elisa R. DonnardORCID

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2 papers

Recent·Most cited

Single Cell Transcriptomics Reveals Dysregulated Cellular and Molecular Networks in a Fragile X Syndrome Model

Elisa R. Donnard, Huan Shu, Manuel G. Garber

This study uses single-cell RNA sequencing to analyze a FXS mouse model, revealing cell-type specific dysregulation and potential mTOR pathway differences.

PLoS Genetics · Jun 8, 2022Peer-reviewedGenomics

FMRP Links Optimal Codons to mRNA stability in Neurons

Huan Shu, Elisa R. Donnard, Botao Liu, Suna Jung, Ruijia Wang, Joel D. Richter

This study shows FMRP stabilizes mRNAs with optimal codons in neurons, linking codon usage to mRNA stability and contributing to FXS pathogenesis.

Proceedings of the National Academy of Sciences · Nov 16, 2020Peer-reviewedMolecular Biology