FMRP Links Optimal Codons to mRNA stability in Neurons
Huan Shu, Elisa R. Donnard, Botao Liu, Suna Jung, Ruijia Wang, Joel D. Richter
This study shows FMRP stabilizes mRNAs with optimal codons in neurons, linking codon usage to mRNA stability and contributing to FXS pathogenesis.
Proceedings of the National Academy of Sciences · Nov 16, 2020Peer-reviewedMolecular Biology