GenomicsThe EMBO JournalPeer-reviewed
Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven β-cell gene expression defects
Khushdeep Bandesh, Efthymios Motakis, Siddhi Nargund…·Michael L. Stitzel
The paper analyzes single-cell transcriptomes of human islet cells across glycemic states to identify gene expression defects in beta cells associated with type 2 diabetes.