Author

Siddhi Nargund

The Jackson Laboratory for Genomic MedicineORCID 0009-0009-9943-0628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Khushdeep BandeshiD· 2 shared Michael L. StitzeliD· 2 shared Romy KursaweiD· 2 shared Alexey I. NesvizhskiiiD· 1 shared Amelia WillettiD· 1 shared AnsarullahiD· 1 shared Cassandra Nichole SprackleniD· 1 shared Chun-Shik ShiniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenomics

Khushdeep BandeshORCID

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3 papers

Recent·Most cited

GenomicsThe EMBO JournalPeer-reviewedApr 15, 2026

Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven β-cell gene expression defects

Khushdeep Bandesh, Efthymios Motakis, Siddhi Nargund…·Michael L. Stitzel

The paper analyzes single-cell transcriptomes of human islet cells across glycemic states to identify gene expression defects in beta cells associated with type 2 diabetes.

22 citationstop 1%

humanscRNA-seq

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ImmunologyThe Journal of ImmunologyPeer-reviewedDec 12, 2025

Tissue signatures of human macrophages during homeostasis and activation

Daniel P. Caron, William L. Specht, Siddhi Nargund…·Donna L. Färber

This study identifies tissue-specific transcriptional and protein profiles of human macrophages in various organs during homeostasis and activation, showing homology to mouse macrophages and responsiveness to cytokine stimuli.

3 citations

humanscRNA-seq

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Cell BiologyNature MetabolismPeer-reviewedJul 21, 2025

LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes

Jin Li, Yamei Deng, Marie Gasser…·Scott A. Soleimanpour

This study identifies LONP1's role in mitochondrial protein folding and shows its impact on beta cell survival and hyperglycemia in type 2 diabetes.

28 citationstop 1%

humanmouse

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