Long-chain polyphosphates induce glomerular microthrombi and exacerbate LPS-induced acute kidney injury in mouse
Anniina Pirttiniemi, Hanne Salmenkari, Krishna A. Adeshara, Jere Lindén, Sanna Lehtonen, Niina Sandholm, Per‐Henrik Groop, Markku J. Lehto
This study shows that long-chain polyphosphates cause kidney damage and worsen LPS-induced acute kidney injury in mice by forming microthrombi and increasing inflammation.
Disease Models & Mechanisms · Feb 6, 2026Peer-reviewedPathology