Niina Sandholm

The paper identifies DNA methylation changes linked to cumulative hyperglycaemia in type 1 diabetes and links some to diabetic kidney disease through Mendelian randomization.

This study shows that long-chain polyphosphates cause kidney damage and worsen LPS-induced acute kidney injury in mice by forming microthrombi and increasing inflammation.

The paper identifies 52 genome-wide associations for urinary metabolites and finds causal relationships between eGFR and 13 metabolites.

The paper identifies DNA methylation biomarkers associated with diabetic kidney disease progression in type 1 diabetes using a prospective cohort study.

The paper uses whole-genome sequencing to identify genetic variants associated with stroke in type 1 diabetes and finds replication evidence for several loci in both diabetic and non-diabetic populations.

The paper identifies novel protein-altering variants associated with serum apolipoprotein and lipid levels using whole-exome and whole-genome sequencing data from individuals with type 1 diabetes.

The paper identifies a genetic variant that affects transcription factor binding and reduces type 1 diabetes risk in infants by altering thymic gene expression.

The paper identifies differentially methylated loci in individuals with end-stage kidney disease due to diabetic kidney disease, linking them to key pathways and genes.

This study identifies 16 genome-wide significant loci associated with diabetic kidney disease, including a protective variant in the COL4A3 gene.