Author

Matthew James Armstrong

Queen Elizabeth Hospital BirminghamORCID 0000-0002-3425-1161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahmed Mohamed ElsharkawyiD· 2 shared Amritpal DhaliwaliD· 2 shared Carolyn Anne GreigiD· 2 shared Felicity Rhian WilliamsiD· 2 shared Janet M. LordiD· 2 shared Jonathan Iain QuinlaniD· 2 shared Leigh BreeniD· 2 shared Simon Wyn JonesiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Ahmed Mohamed ElsharkawyORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Cachexia Sarcopenia and MusclePeer-reviewedApr 26, 2026

Systemic drivers and molecular mechanisms of sarcopenia in aetiology-specific end-stage liver disease

Thomas Nicholson, S. Allen, Jonathan Iain Quinlan…·Simon Wyn Jones

This study identifies aetiology-specific molecular mechanisms of sarcopenia in end-stage liver disease by analyzing transcriptomic changes and cytokine profiles in muscle and plasma.

DOI 10.1002/jcsm.70294

humanbulk RNA-seq

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PhysiologyGeroSciencePeer-reviewedNov 14, 2025

Increased Quadriceps Intermuscular Adipose Tissue in Chronic Liver Disease is Associated with an Altered Muscle Transcriptome compared with Healthy Age Matched Controls.

Jonathan Iain Quinlan, T. Nicholson, C. Bell…·Leigh Breen

This study finds increased intermuscular adipose tissue in chronic liver disease patients compared to controls, associated with altered muscle gene expression and reduced muscle function.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky