Author

T. Nicholson

University Hospitals Birmingham NHS Foundation Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kothandapani· 1 shared A. Philp· 1 shared A. Theberge· 1 shared Ahmed Mohamed ElsharkawyiD· 1 shared Alex V. RowlandsiD· 1 shared Amritpal DhaliwaliD· 1 shared C. Bell· 1 shared C. Jefcoate· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A. Kothandapani

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3 papers

Recent·Most cited

Increased Quadriceps Intermuscular Adipose Tissue in Chronic Liver Disease is Associated with an Altered Muscle Transcriptome compared with Healthy Age Matched Controls.

Jonathan Iain Quinlan, T. Nicholson, C. Bell, Amritpal Dhaliwal, Felicity Rhian Williams, Steven L. Allen, Surabhi Choudhary, Alex V. Rowlands, Ahmed Mohamed Elsharkawy, Matthew James Armstrong, Carolyn Anne Greig, Janet M. Lord, Simon Wyn Jones, Leigh Breen

This study finds increased intermuscular adipose tissue in chronic liver disease patients compared to controls, associated with altered muscle gene expression and reduced muscle function.

GeroScience · Nov 14, 2025Peer-reviewedPhysiology

Protein-carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle

N. Hodson, J. R. Dent, Z. Song, M. O'Leary, T. Nicholson, S. W. Jones, J. Murray, S. Jeromson, D. L. Hamilton, L. Breen, A. Philp

This study shows that protein-carbohydrate ingestion in human skeletal muscle increases Vps34 translocation to the cell periphery and its co-localization with mTOR, without altering Vps34 kinase activity or preventing mTORC1 activation.

bioRxiv · Feb 10, 2020Physiology

Injection molded open microfluidic well plate inserts for user-friendly coculture and microscopy

J. H. Day, T. Nicholson, X. Su, T. Van Neel, I. Clinton, A. Kothandapani, J. Lee, M. Greenberg, J. Amory, T. Walsh, C. Muller, O. Franco, C. Jefcoate, S. Crawford, J. Jorgensen, A. Theberge

The paper introduces injection molded open microfluidic devices for coculture and microscopy, enabling study of cell interactions in standard cell culture workflows.

bioRxiv · Nov 4, 2019Bioengineering