Author

Lakshmi Swarna Mukhi Pidugu

University of Maryland, BaltimoreORCID 0000-0002-3426-9003Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexander C. DrohatiD· 1 shared Baiyu Zhu· 1 shared E. A. P. Tharaka Amarasekara· 1 shared Jérôme S. MenetiD· 1 shared Jonathan T. SczepanskiiD· 1 shared Mary E. CookiD· 1 shared Xinyu Nie· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alexander C. DrohatORCID

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1 paper

Recent·Most cited

Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids

Baiyu Zhu, Lakshmi Swarna Mukhi Pidugu, Mary E. Cook, Xinyu Nie, E. A. P. Tharaka Amarasekara, Jérôme S. Menet, Alexander C. Drohat, Jonathan T. Sczepanski

This study shows that TDG binds R-loops and removes 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids, supporting a role for R-loops in DNA demethylation.

Journal of Biological Chemistry · Feb 26, 2026Peer-reviewedBiochemistry