The Tricuspid Valve is Transcriptionally Active During Prolonged Pressure Overload, Right-Sided Heart Failure, and Valve Regurgitation
Austin Goodyke, Bogusław Gawęda, Magda Piekarska, Sanjana Arora, Mason Westgate, Renzo Y. Loyaga‐Rendon, Milena Jani, Manuel K. Rausch, Aitor Aguirre, Jeremy W. Prokop, Tomasz A. Timek
This paper uses a sheep model of right-sided heart failure to identify transcriptional changes in the tricuspid valve and other cardiac tissues, highlighting sex-specific and disease-related gene expression patterns.
Journal of the American Heart Association · Jan 30, 2026Peer-reviewedGenomics