Bogusław Gawęda

Incomplete Reverse Remodeling of the Tricuspid Valve Leaflets Following Relief of Pressure Overload

This paper investigates tricuspid valve leaflet remodeling in response to and after relief of right ventricular pressure overload in sheep, finding that leaflets do not fully revert to normal despite hemodynamic normalization.

Sex-Specific Remodeling Phenotypes of the Tricuspid Valve Leaflets in an Ovine Model of Functional Tricuspid Regurgitation

This study investigates sex-specific tricuspid valve leaflet remodeling in an ovine model of functional tricuspid regurgitation, revealing distinct structural, mechanical, and transcriptional responses across sexes and castration status.

The Tricuspid Valve Maladapts in a Pulmonary Hypertension Rat Model

This study shows that tricuspid valve remodeling occurs in a rat pulmonary hypertension model, with structural changes rather than intrinsic stiffening driving the maladaptation.

The Tricuspid Valve is Transcriptionally Active During Prolonged Pressure Overload, Right-Sided Heart Failure, and Valve Regurgitation

This paper uses a sheep model of right-sided heart failure to identify transcriptional changes in the tricuspid valve and other cardiac tissues, highlighting sex-specific and disease-related gene expression patterns.

Tricuspid valve leaflet remodeling in sheep with biventricular heart failure: A comparison between leaflets

This study compares tricuspid valve leaflet remodeling in a sheep model of biventricular heart failure, finding that the anterior leaflet undergoes the most significant changes while the septal and posterior leaflets show less pronounced but similar remodeling.