Tomasz A. Timek

This study compares Clover and Zipping techniques in tricuspid edge-to-edge repair, finding that Clover reduces septal-lateral annular diameter more effectively.

This paper develops a framework to predict tricuspid valve deformation without needing in vivo chordal geometry, using shape-matching and stress-based calibration to generate synthetic chordae.

This paper investigates tricuspid valve leaflet remodeling in response to and after relief of right ventricular pressure overload in sheep, finding that leaflets do not fully revert to normal despite hemodynamic normalization.

This study investigates sex-specific tricuspid valve leaflet remodeling in an ovine model of functional tricuspid regurgitation, revealing distinct structural, mechanical, and transcriptional responses across sexes and castration status.

This study shows that tricuspid valve remodeling occurs in a rat pulmonary hypertension model, with structural changes rather than intrinsic stiffening driving the maladaptation.

This study investigates how TEER-induced annular forces affect the annuloplasty effect in tricuspid valves using computational simulations.

This study measures annular forces from TEER in porcine hearts, finding that force magnitude varies with clip placement and number of clips.

This paper uses a sheep model of right-sided heart failure to identify transcriptional changes in the tricuspid valve and other cardiac tissues, highlighting sex-specific and disease-related gene expression patterns.

This study compares tricuspid valve leaflet remodeling in a sheep model of biventricular heart failure, finding that the anterior leaflet undergoes the most significant changes while the septal and posterior leaflets show less pronounced but similar remodeling.

The paper uses single-cell RNA sequencing to identify CD8+/CD52+ NKT cells as a survival predictor in patients on VA-ECLS, showing their inverse correlation with IL-6 production.