Manuel K. Rausch

This study compares Clover and Zipping techniques in tricuspid edge-to-edge repair, finding that Clover reduces septal-lateral annular diameter more effectively.

This paper develops a framework to predict tricuspid valve deformation without needing in vivo chordal geometry, using shape-matching and stress-based calibration to generate synthetic chordae.

This study compares constitutive neural network predictions of fiber dispersion in the right ventricle with experimental data, showing that multi-axial loading improves parameter identifiability.

This study investigates sex-specific tricuspid valve leaflet remodeling in an ovine model of functional tricuspid regurgitation, revealing distinct structural, mechanical, and transcriptional responses across sexes and castration status.

This study shows that arterial-like flow alters fibrin structure, reduces molecular transport, and decreases binding of fibrinolytic enzymes like Plg and tPA.

This study investigates the mechanical and biological changes in mouse pressure ulcers over time, showing how tissue deformation, inflammation, and collagen remodeling co-evolve during ulcer formation and healing.

This study shows that tricuspid valve remodeling occurs in a rat pulmonary hypertension model, with structural changes rather than intrinsic stiffening driving the maladaptation.

This study investigates how TEER-induced annular forces affect the annuloplasty effect in tricuspid valves using computational simulations.

This study shows MRI can predict blood clot composition and contraction state using radiomic features, supporting its use for pre-interventional clot phenotyping.

This study measures annular forces from TEER in porcine hearts, finding that force magnitude varies with clip placement and number of clips.

This paper uses a sheep model of right-sided heart failure to identify transcriptional changes in the tricuspid valve and other cardiac tissues, highlighting sex-specific and disease-related gene expression patterns.

This study compares co-electrospinning and blend electrospinning of polycaprolactone and SIS for bone wrap fabrication, showing co-spun wraps improve handling, infection control, and angiogenesis.

This study investigates how fibrinogen levels and white blood cell subtypes, along with hematocrit and sex, influence in vitro blood clot mechanical properties.

This study assesses inter-laboratory variability in mechanical property characterization of porcine aorta through two testing rounds, highlighting persistent discrepancies despite protocol standardization.

This study shows fibrin fibers exhibit viscoelastic behavior and irreversible damage under cyclic loading, with damage sources identified through molecular analysis.

This study compares tricuspid valve leaflet remodeling in a sheep model of biventricular heart failure, finding that the anterior leaflet undergoes the most significant changes while the septal and posterior leaflets show less pronounced but similar remodeling.

This paper develops a self-fitting vaginal stent using shape-memory polymer foams that expand at body temperature to prevent vaginal stenosis, demonstrating effective shape recovery and retention in a simulated model.