The Swiss Army Knife of Alginate Manipulation - A Gut Bacterium Alginate Lyase with Diverse Catalytic Activities
Tobias Tandrup, José Pablo Rivas-Fernández, Mikkel Gulmann Madsen, Mette E. Rønne, Agnes Beenfeldt Petersen, Leesa J. Klau, Anne Tøndervik, Casper Wilkens, Finn L. Aachmann, Carme Rovira, Birte Svensson
This paper characterizes the alginate lyase BoPL38 from Bacteroides ovatus, revealing its dual catalytic activities and structural mechanisms for alginate degradation and epimerization.
Journal of the American Chemical Society · Jun 26, 2025Peer-reviewedBiochemistry