Author

Jaime Fernandez-Macgregor

Centre National de la Recherche ScientifiqueORCID 0000-0002-2494-6541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Andreas ZanzoniiD· 2 shared Christine BruniD· 2 shared Fabien DurbessoniD· 2 shared Lou BergogneiD· 2 shared Renaud VincentelliiD· 2 shared Achille BroggiiD· 1 shared Andrew Philip RennisoniD· 1 shared Aurélie BergoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Andreas ZanzoniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A quantitative interactome map reveals affinity tailored hijacking of human cellular functions by resident and pathogenic bacteria

Jaime Fernandez-Macgregor, Laura Ilari, Fabien Durbesson, Stéphane Audebert, Luc Camoin, Bastien Morlet, Virginie Millet, Jean Michel Dela Vedova-Costa, Charlene Gaedke, Vincent Kourilsky, Lou Bergogne, Eric Martínez, Achille Broggi, Jean‐Paul Borg, Søren Østergaard, , Renaud Vincentelli

The paper reports a large-scale quantitative interactome of human PDZ domains and bacterial PDZ-binding motifs, showing bacteria tailor effector sequences to bind with similar or higher affinity than human PBMs to hijack host functions.

bioRxiv · Oct 5, 2026 · PreprintSystems Biology

BactMentha: a database of annotated bacteria-host protein interactions

Lou Bergogne, Mégane Boujeant, Marta Iannuccelli, Aurélie Bergon, Jaime Fernandez-Macgregor, Christine Brun, Luana Licata, Andreas Zanzoni

BactMentha is a database of annotated bacteria-host protein interactions for human, mouse, and rat, including virulence proteins and predicted interaction interfaces.

bioRxiv · Oct 5, 2026 · PreprintBioinformatics

A high throughput investigation of the binding specificity of carbohydrate-binding modules for synthetic and natural polymers

Andrew Philip Rennison, Jaime Fernandez-Macgregor, Julie Melot, Fabien Durbesson, Tobias Tandrup, Peter Westh, Renaud Vincentelli, Marie Sofie Møller

This paper develops a high-throughput screening pipeline to identify carbohydrate-binding modules (CBMs) that bind synthetic and natural polymers, discovering binders for PET, PE, PS, and polysaccharides, and demonstrating their utility in enhancing plastic-degrading enzyme activity.

ChemSusChem · Jun 19, 2025Peer-reviewedBioengineering