Author

Maheswarareddy Emani

Broad InstituteORCID 0000-0002-3455-1818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alyssa B. FanelliiD· 1 shared Amy D. Westerling-BuiiD· 1 shared Anna GrekaiD· 1 shared Anthony AntonelliiD· 1 shared Astrid WeinsiD· 1 shared Aviv RegeviD· 1 shared Ayshwarya SubramanianiD· 1 shared Baixue XiaoiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperGenomics

Alyssa B. FanelliORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 26, 2025

Predictive in vitro profiling of LNP-induced innate immune response using an iPSC-derived monocyte model

Baixue Xiao, Soojin Kim, Benjamin I Laufer…·Maheswara Reddy Emani

This study develops an iPSC-derived monocyte model to predict LNP-induced innate immune responses, showing improved reproducibility and correlation with in vivo cytokine responses.

DOI 10.1101/2025.09.26.678842

humanexperimental assay

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GenomicsbioRxivPreprintDec 30, 2019

A translational kidney organoid system bolsters human relevance of clinical development candidate

Amy D. Westerling-Bui, Thomas W. Soare, Srinivasan P Venkatachalan…·Peter H. Mundel

The paper develops a high-throughput human kidney organoid platform for drug screening, validated by scRNA-Seq and showing protective effects of CsA and GFB-887 against kidney injury.

2 citations

humanscRNA-seq

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GenomicsNature CommunicationsPeer-reviewedNov 29, 2019

Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics

Ayshwarya Subramanian, Eriene-Heidi Sidhom, Maheswarareddy Emani…·Anna Greka

The paper uses single-cell RNA-Seq to assess kidney organoid reproducibility across iPSC lines and shows transplantation reduces off-target cells.

212 citationstop 1%

humanscRNA-seq

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