Author

Cristina Nieto‐Jiménez

Hospital Clínico San CarlosORCID 0000-0002-3463-1439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Alberto OcañaiD· 2 shared Jorge Reñe EspinosaiD· 2 shared Alejandro FeitoiD· 1 shared Andrés R. TejedoriD· 1 shared Atanasio PandiellaiD· 1 shared Balázs GyőrffyiD· 1 shared Bernard Doger· 1 shared Carlos Alonso‐MorenoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Alberto OcañaORCID

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2 papers

Recent·Most cited

LGR5-high colorectal cancer defines a Wnt-active stem-like state with multimodal therapeutic vulnerabilities

Lucía Paniagua‐Herranz, Alejandro Feito, Cristian Privat, Luis Álvarez‐Carrión, Bernard Doger, Andrés R. Tejedor, Juan Antonio Ardua, Verónica Alonso, Cristina Nieto‐Jiménez, Carlos Alonso‐Moreno, Victor Moreno, Emiliano Calvo, Balázs Győrffy, Jorge R. Espinosa, Alberto Ocaña

The paper identifies LGR5-high colorectal cancer as a Wnt-active stem-like state with therapeutic vulnerabilities across multiple modalities.

bioRxiv · Oct 5, 2026 · PreprintMolecular Biology

Computational mapping of antibody-receptor energy landscapes to predict membrane internalization

Pablo Burriel Llombart, Cristina Nieto‐Jiménez, Atanasio Pandiella, Alberto Ocaña, Jorge Reñe Espinosa

This study uses molecular dynamics simulations to predict antibody internalization by mapping energy landscapes between antibodies and JAM-A receptors, identifying key interactions that drive endocytosis.

bioRxiv · Mar 25, 2026 · PreprintBiophysics